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Chaetocin

CAT: 0400-SIH-351-200UGSize: 200 µgDry Ice: NoHazardous: No
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CAT#:0400-SIH-351-200UGSize:200 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Inhibits the lysine methyltransferase SU (VAR)3-9. Displays antimyeloma activity in IL-6-dependent myeloma cell lines. Cell permeable.
Description
Methyltransferase inhibitor
CAS Number
28097-03-2
Product Name Alternative
2, ​2', ​3S, ​3'S, ​5aR, ​5'aR, ​6, ​6'-​octahydro-​3, ​3'-​bis (hydroxymethyl) -​2, ​2'-​dimethyl-​[10bR, ​10'bR (11aS, ​11'aS) -​bi-​3, ​11a-​epidithio-​11aH-​pyrazino[1', ​2':1, ​5]pyrrolo[2, ​3-​b]indole]-​1, ​1', ​4, ​4'-​tetrone
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Epigenetics and Nuclear Signaling | Cancer
Purity
>99% (TLC), NMR conforms
Weight
0.0002
Format
Lyophilized Solid
Solubility
Soluble in 25 mg/ml DMSO or 25 mg/ml Ethanol
Molecular Formula
C30H28N6O6S4
Molecular Weight
696.9
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Greiner D., et al. (2005) Nat Chem Biol. 1: 143. 2. Isham, C.R., et al. (2007) Blood. 109: 2579.

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A4502-10Chaetocin
TBZ2883Chaetocin A

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