Amlodipine

• Background :

  Amlodipine is a long-acting calcium channel blocker used as an anti-hypertensive and in the treatment of angina. It acts by relaxing the smooth muscle in the arterial wall, decreasing total peripheral resistance and hence reducing blood pressure.

• Description :

  L-type Ca channel blocker

• Product Name Alternative :

  3-Ethyl 5-methyl 2-[ (2-aminoethoxy) methyl]-4- (2-chlorophenyl) -6-methyl-1,4-dihydro-3,5-pyridinedicarboxylate, Norvasc

• UNSPSC :

  41116105

• Type :

  Inhibitor

• Source :

  Synthetic

• Field of Research :

  Neuroscience | Ion Channels | Calcium Channels | Voltage-Gated Calcium Channels

• Purity :

  >98%

• Weight :

  0.05

• Format :

  White Solid

• Solubility :

  Soluble to 100 mM in DMSO and to 10 mM in water

• Molecular Formula :

  C20H25ClN2O5•C6H5SO3H

• Molecular Weight :

  567.05

• Precautions :

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations :

  1. Luksa J., Josic D., Kremser M., Kopitar Z and Milutinovic S. (1997) J Chromatorgraphy. B, Biomed Sci and App. 693(2): 367-375. 2. Bahl V.K., Jadhav U.M., Thacker H.P. (2009) Am J Cardiovasc Drugs. 9(3): 135-142.

• CAS Number :

  111470-99-6