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Amlodipine

CAT: 0400-SIH-315-250MGSize: 250 mgDry Ice: NoHazardous: No
CAT#:0400-SIH-315-250MGSize:250 mg
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Background
Amlodipine is a long-acting calcium channel blocker used as an anti-hypertensive and in the treatment of angina. It acts by relaxing the smooth muscle in the arterial wall, decreasing total peripheral resistance and hence reducing blood pressure.
Description
L-type Ca channel blocker
CAS Number
111470-99-6
Product Name Alternative
3-Ethyl 5-methyl 2-[ (2-aminoethoxy) methyl]-4- (2-chlorophenyl) -6-methyl-1,4-dihydro-3,5-pyridinedicarboxylate, Norvasc
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Neuroscience | Ion Channels | Calcium Channels | Voltage-Gated Calcium Channels
Purity
>98%
Weight
0.25
Format
White Solid
Solubility
Soluble to 100 mM in DMSO and to 10 mM in water
Molecular Formula
C20H25ClN2O5•C6H5SO3H
Molecular Weight
567.05
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Luksa J., Josic D., Kremser M., Kopitar Z and Milutinovic S. (1997) J Chromatorgraphy. B, Biomed Sci and App. 693(2): 367-375. 2. Bahl V.K., Jadhav U.M., Thacker H.P. (2009) Am J Cardiovasc Drugs. 9(3): 135-142.

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