Products for Research Use Only

Dofetilide

CAT: 0400-SIH-311-10MGSize: 10 mgDry Ice: NoHazardous: No
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CAT#:0400-SIH-311-10MGSize:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Dofetilide is a class III antiarrhythnic agent (1). It works by selectively blocking the rapid component of the delayed rectifier outward potassium current (2).
Description
Herg channel blocker
CAS Number
115256-11-6
Product Name Alternative
N- (4-{2-[Methyl (2-{4-[ (methylsulfonyl) amino]phenoxy}ethyl) amino]ethyl}phenyl) methanesulfonamide, Tikosyn, UK 68798
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Neuroscience | Ion Channels
Purity
>98%
Weight
0.01
Format
White Solid
Solubility
Soluble to 100 mM in DMSO
Molecular Formula
C19H27N3O5S2
Molecular Weight
441.56
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Lentz T.L., Hilleman D.E. (2000) Pharmacotherapy. 20(7): 776-786. 2. Roukoz H., Saliba W. (2007) Expert Rev Cardiovasc Ther. 5(1): 9-19.

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