AP-18

• Background:

  AP-18 is a reversible TRPA1 channel blocker. They exhibit fibroblast-like morphology, slow growth and contact inhibition (1).

• Description:

  TRPA1 blocker

• Product Name Alternative:

  (2E,3E) -4- (4-Chlorophenyl) -N-hydroxy-3-methyl-3-buten-2-imine

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Neuroscience | Ion Channels | Transient Receptor Potential (TRP) Channels

• Purity:

  >98%

• Weight:

  0.01

• Format:

  White Solid

• Solubility:

  Soluble to 100 mM in DMSO and to 100 mM in ethanol

• Molecular Formula:

  C11H12ClNO

• Molecular Weight:

  209.67

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Doi H., et al. (2005) Tohoku J Exp Med. 207(3): 209-216.

• CAS Number:

  55224-94-7