Anisomycin

• Background:

  Anisomycin is an antibiotic which inhibits protein synthesis (1). It interferes with protein and DNA synthesis by inhibiting peptidyl transferace on the 80S ribosome system. It can activate stress-activated protein kinases, MAPkinase and other signal transduction pathways.

• Description:

  P38 MAP kinase activator

• Product Name Alternative:

  (2S,3R,4R) -4-Hydroxy-2- (4-methoxybenzyl) -3-pyrrolidinyl acetate

• UNSPSC:

  41116105

• Type:

  Activator

• Source:

  Synthetic

• Field of Research:

  Cancer | Apoptosis

• Purity:

  >98%

• Weight:

  0.05

• Format:

  White solid

• Solubility:

  Soluble to 100 mM in DMSO and to 100 mM in ethanol

• Molecular Formula:

  C14H19NO4

• Molecular Weight:

  265.31

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Grollman A.P. (1967) J Biol Chem. 242(13): 3226-3233.

• CAS Number:

  22862-76-6