Resveratrol

• Background:

  Resveratrol is a stilbenoid and a phytoalexin produced naturally by several plants. Its effects are numerous and include anti-cancer (1), anti-inflammatory (2), anti-fungal and has other beneficial cardiovascular effects. It has been proposed that Mn SOD is increased by the pathwayRESV-SIRT1/Nad+- FOXO3a- MnSOD (3). In terms of its anti-cancer properties, resveratrol modulates the transcription factor NF-KB and inhibition of the cytochrome P450 enzyme (1, 4). It also enhances hippocampal neurogenesis.

• Description:

  Antioxidant

• Product Name Alternative:

  5-[ (E) -2- (4-Hydroxyphenyl) vinyl]-1,3-benzenediol

• UNSPSC:

  41116105

• Type:

  Antioxidant

• Source:

  Synthetic

• Field of Research:

  Cancer | Apoptosis | Neuroscience | Neurodegeneration | Neurogenesis

• Purity:

  >98%

• Weight:

  0.1

• Format:

  Off-White Solid

• Solubility:

  Soluble to 100 mM in DMSO and to 100 mM in ethanol

• Molecular Formula:

  C14H12O3

• Molecular Weight:

  228.25

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Leiro J., et al. (2005) Int Immunopharm. 5(2): 393-406. 2. Gentilli M., et al. (2001) Life Sciences. 68(11): 1317-1321. 3. Robb E.L., et al. (2008) Biochem Biophys Res Commun. 367(2): 406-412. 4. Chun Y.J., Kim M.Y., Guengerich F.P. (1999) Biochem Biophys Res Commun. 262(1): 20-24.

• CAS Number:

  501-36-0