Simvastatin

• Background:

  Simvastatin is a member of the drug class of statins, used for lowering cholersterol, thereby preventing cardiovascular disease. They have a powerful inhibitory effect on HMG-CoA reducatse (1).

• Description:

  HMG-CoA reductase inhibitor

• Product Name Alternative:

  (1S,3R,7S,8S,8aR) -8-{2-[ (2R,4R) -4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-1-naphthalenyl 2,2-dimethylbutanoate

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Cancer | Apoptosis

• Purity:

  >98%

• Weight:

  0.05

• Format:

  White solid

• Solubility:

  Soluble to 75 mM in ethanol and 50 mM in DMSO

• Molecular Formula:

  C25H38O5

• Molecular Weight:

  418.57

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Alberts A.W. (1998) Am J Cardio. 62(15): 10J-15J.

• CAS Number:

  79902-63-9