Hypericin

• Background:

  Hypericin is a naphtodianthrone that acts as an antibiotic and non-specific kinase inhibitor. It inhibits the action of dopamine beta-hydroxylase, leading to increased dopamine levels. Hypericin can also cause photosensitivity when ingested beyond threshold. And becase it also accumulates in cancerous tissues, it can be used as an indicator of cancerous cells (1, 2).

• Description:

  Protein kinase C inhibitor

• Product Name Alternative:

  1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-7,14-dione

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

• Purity:

  >98%

• Weight:

  0.001

• Format:

  Dark Red Solid

• Solubility:

  Soluble to 10 mM in ethanol and to 50 mM in DMSO

• Molecular Formula:

  C30H16O8

• Molecular Weight:

  504.45

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Hopfner M., et al. (2003) Int J Colorectal Dis. 18(3): 239-247. 2. Agostinis, et al. (2002) Int J Biochem Cell Biol. 34: 221.

• CAS Number:

  548-04-9