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Hypericin

CAT: 0400-SIH-250-1MGSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0400-SIH-250-1MGSize:1 mg
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Background
Hypericin is a naphtodianthrone that acts as an antibiotic and non-specific kinase inhibitor. It inhibits the action of dopamine beta-hydroxylase, leading to increased dopamine levels. Hypericin can also cause photosensitivity when ingested beyond threshold. And becase it also accumulates in cancerous tissues, it can be used as an indicator of cancerous cells (1, 2).
Description
Protein kinase C inhibitor
CAS Number
548-04-9
Product Name Alternative
1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-7,14-dione
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors
Purity
>98%
Weight
0.001
Format
Dark Red Solid
Solubility
Soluble to 10 mM in ethanol and to 50 mM in DMSO
Molecular Formula
C30H16O8
Molecular Weight
504.45
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Hopfner M., et al. (2003) Int J Colorectal Dis. 18(3): 239-247. 2. Agostinis, et al. (2002) Int J Biochem Cell Biol. 34: 221.

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