Cycloheximide

• Background:

  Selective inhibitor of eukaryotic protein synthesis blocking tRNA binding and release from ribosomes. Induces apoptosis in a variety of transformed and normal cell lines, including T-cells.

• Description:

  Translation inhibitor

• Product Name Alternative:

  4-{ (2R) -2-[ (1S,3S,5S) -3,5-Dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}-2,6-piperidinedione

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Cancer | Apoptosis

• Purity:

  >98%

• Weight:

  5

• Format:

  White solid

• Solubility:

  Soluble to 50 mM in Ethanol and 25 mM in water

• Molecular Formula:

  C15H23NO4

• Molecular Weight:

  281.35

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Obrig T.G., et al. (1971) J Biol Chem. 246:174.

• CAS Number:

  66-81-9