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Docetaxel

CAT: 0400-SIH-240-10MGSize: 10 mgDry Ice: NoHazardous: No
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CAT#:0400-SIH-240-10MGSize:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Docetaxel is a semi-synthetic analogue of paclitaxel differing at two positions in its chemical structure (1). It also binds and stabilizes microtubules which leads to cell cycle arrest and apoptosis (2).
Description
Microtubule stabilizer
CAS Number
114977-28-5
Product Name Alternative
(2α,5β,7β,10β,13α) -4-Acetoxy-1,7,10-trihydroxy-13-{[ (2R,3S) -2-hydroxy-3- ({[ (2-methyl-2-propanyl) oxy]carbonyl}amino) -3-phenylpropanoyl]oxy}-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
UNSPSC
41116105
Type
Inducer
Source
Synthetic
Field of Research
Cancer | Apoptosis
Purity
>98%
Weight
0.01
Format
White solid
Solubility
Soluble to 100 mM in DMSO, and to 100 mM in ethanol
Molecular Formula
C43H53NO14
Molecular Weight
807.88
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Clarke S.J., and Rivory L.P. (1999) Clin Pharmacokinet. 36(2): 99-114. 2. Woodward E.J. and Twelves C. (2010) Curr. Clin Pharmacol. 5(3): 226-231.

Alternative Products

CatalogName
A4394-50Docetaxel

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