RegisterLogin

Nigericin

CAT: 0400-SIH-229-10MGSize: 10 mgDry Ice: NoHazardous: No
CAT#:0400-SIH-229-10MGSize:10 mg
Selected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Nigericin acts as a K and Na ionophore. It stimulates Ca release from mitochondrial stores by disruption of membrane potential.
Description
NALP3 activator
CAS Number
28643-80-3
Product Name Alternative
(2R) -2-[ (2R,3S,6R) -6-{[ (2S,4R,5R,7R,9R,10R) -2-{ (2S,2'R,3'S,5R,5'R) -5'-[ (2S,3S,5R,6R) -6-Hydroxy-6- (hydroxymethyl) -3,5-dimethyltetrahydro-2H-pyran-2-yl]-2,3'-dimethyloctahydro-2,2'-bifuran-5-yl}-9-metho xy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]dec-7-yl]methyl}-3-methyltetrahydro-2H-pyran-2-yl]propanoic acid
UNSPSC
41116105
Type
Inducer
Source
Synthetic
Field of Research
Cancer | Apoptosis
Purity
>98%
Weight
0.01
Format
White to off-white Solid
Solubility
Soluble to 50 mM in DMSO and 20 mM in ethanol
Molecular Formula
C40H67NaO11
Molecular Weight
746.94
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Vercesi A.E., et al. (1993) J Biol Chem. 268: 8564. 2. Graven S.N., Estrada-O, S., Lardy H.A. (1966) Proc Natl Acad Sci USA. 56(2): 654-658.

Related Products

CatalogName

Alternative Products

CatalogName
N039-25MGNigericin
6698Nigericin
HY-127019-01Nigericin
BA1112-10Nigericin
T16323-01Nigericin
35779-34Nigericin
BITP3218Nigericin
tlrl-nigNigericin
BA1112-5Nigericin
MBS5769690Nigericin

Popular Products