PK-11195

• Background :

  PK-11195 is an isoquinoline carboxamide which binds selectively to the peripheral benzodiazepine receptor (PBR). It has a high affinity for the PBR in all species (1). It has also been successfully used in PET scans to visualize brain inflammation in patients with neuronal damage (2).

• Description :

  Mitochondrial Benzodiazepine receptor ligand

• Product Name Alternative :

  N-sec-Butyl-1- (2-chlorophenyl) -N-methyl-3-isoquinolinecarboxamide

• UNSPSC :

  41116105

• Type :

  Inducer

• Source :

  Synthetic

• Field of Research :

  Cancer | Apoptosis

• Purity :

  >98%

• Weight :

  0.005

• Format :

  White Crystals

• Solubility :

  Soluble to 75 mM in ethanol and to 100 mM in DMSO

• Molecular Formula :

  C21H21CIN2O

• Molecular Weight :

  352.86

• Precautions :

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations :

  1. Pike V.W., et al. (1993) Nucl Med & Bio. 20(4): 503-525. 2. Buck J.R., et al. (2011) J Nucl Med. 52(1): 107-114.

• CAS Number :

  85532-75-8