Andrographolide

• Background :

  Andrographolide is a labdane diterpenoid that is the main bioactive component of the medicinal plant Andrographis paniculata. Is has been shown to be effective against certain cancers, and is an effective purgative (1). It blocks T-cell proliferation to allogenic stimuli and the chemotactic migration of macrophages induced by complement (2, 3).

• Description :

  Apoptosis Inducer

• CAS Number :

  5508-58-7

• Product Name Alternative :

  (3E) -4-Hydroxy-3-{2-[ (1R,4aS,6R,8aS) -6-hydroxy-5- (hydroxymethyl) -5,8a-dimethyl-2-methylenedecahydro-1-naphthalenyl]ethylidene}dihydro-2 (3H) -furanone

• UNSPSC :

  41116105

• Type :

  Inducer

• Source :

  Synthetic

• Field of Research :

  Cancer | Apoptosis

• Purity :

  >98%

• Weight :

  0.5

• Format :

  Off-white Solid

• Solubility :

  DMSO

• Molecular Formula :

  C20H30O5

• Molecular Weight :

  350.45

• Precautions :

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations :

  1. Chakravarti R.N., Chakravarti D. (1951) Ind. Med Gaz. 86(3): 96-7. 2. Tsai H.R., et al. (2004) Eur J Pharmacol. 498: 45-52. 3. Rajagopal S., et al. (2003) J Exp. Ther. Oncol. 3: 147-158.