U-74389G

• Background:

  U-74389G is an antioxidant which prevents iron-dependent lipid peroxidation. It prevents organ damage in intestinal cold storage, preservation and reperfusion injury (1-4).

• Description:

  Lipid peroxidation blocker

• Product Name Alternative:

  21-{4-[2,6-Di (1-pyrrolidinyl) -4-pyrimidinyl]-1-piperazinyl}pregna-1,4,9 (11) -triene-3,20-dione (2Z) -2-butenedioate (1:1)

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Cancer | Apoptosis

• Purity:

  >99%

• Weight:

  0.5

• Format:

  White Solid

• Solubility:

  Soluble in 25 mg/ml DMSO, and in 20 mg/ml in ethanol; Insoluble in water

• Molecular Formula:

  C37H50N6O2•C4H4O4

• Molecular Weight:

  726.9

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Ishizaki N., et al. (1997) Transplantation. 63: 202-208. 2. Perna A.M., et al. (1996) Pharmacol Res. 34: 25-31. 3. Palma-Vargas J.M., et al. (1996) J Surg Res. 66: 131-137. 4. Shoskes D.A., Xie Y., Gonzalez-Cadavid N.F. Transplantation. 63: 495-500.

• CAS Number:

  153190-29-5