Products for Research Use Only

FCR1

CAT: 0400-SIH-180-1MGSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0400-SIH-180-1MGSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
FCR1 or flavin coumarin redox sensor 1, is a novel ratiometric fluorescent redox sensor utilized in fluorescence lifetime imaging microscopy and flow cytometry. In the oxidized form, excitation of FCR1 at 405nm results in a green fluorescence with max emissions at 525nm. Treatment with a mild reducing agent (including sodium cyanoborohydride, DTT, and glutathione) reduces the flavin thereby decreasing the green fluorescence intensity, and increasing the blue. Re-oxidation can be achieved using mild oxidizing agents. In general, the FCR1 probe can be used to observe changes in oxidative capacity without interference from background effects.
Description
FRET ratiometric fluorescence-based redox sensor
Product Name Alternative
7- (Diethylamino) -N- ((1r,4r) -4- (2- (10-ethyl-2,4-dioxo-4,10-dihydrobenzo[g]pteridin-3 (2H) -yl) acetamido) cyclohexyl) -2-oxo-2H-chromene-3-carboxamide (FCR1)
UNSPSC
41116105
Type
Redox Probe
Source
Synthetic
Field of Research
Cancer | Oxidative Stress
Weight
0.001
Format
Orange Solid
Solubility
Soluble in DMSO
Molecular Formula
C34H37N7O6
Molecular Weight
639
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Kaur A., Haghighatbin M.A., Hogan C.F., and New E.J. (2015) Chem. Commun. Epub.