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Mefuparib

CAT: 0804-HY-167927-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-167927-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mefuparib (CVL218) is a poly ADP-ribose polymerase (PARP) inhibitor used in cancer research that exhibits potent brain penetration due to its high protein binding.
CAS Number
1392502-82-7
Product Name Alternative
CVL218
UNSPSC
12352005
Target
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mefuparib.html
Purity
99.77
Solubility
DMSO : 6.25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CC(F)=CC2=C1OC(C3=CC=C(CNC)C=C3)=C2)N
Molecular Formula
C17H15FN2O2
Molecular Weight
298.31
References & Citations
[1]Absorption, distribution, metabolism, and excretion of [14C]Mefuparib (CVL218), a novel PARP1/2 inhibitor, in rats
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

Alternative Products

CatalogName
T11992-01Mefuparib hydrochloride
GTR19154066-01Mefuparib hydrochloride (CVL218)

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