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C-Kit-IN-8

CAT: 0804-HY-168581Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-168581Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
C-Kit-IN-8 (Compound 53) is an inhibitor for c-Kit kinase, that inhibits uKIT kinase with an IC50 > 1 μM. c-Kit-IN-8 inhibits the proliferation of cancer cell GIST430 and BaF3 wildtype and mutants with IC50 > 0.1 μM[1].
CAS Number
2941024-89-9
UNSPSC
12352101
Target
C-Kit
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/c-kit-in-8.html
Smiles
COCCOC1=CC(F)=C2C(N=CN=C2NC3=CC=C(C=C3)NC(CCN4CCCC4=O)=O)=C1
Molecular Formula
C24H26FN5O4
Molecular Weight
467.49
References & Citations
[1]Ahn YM, et al., Kit kinase inhibitors and methods of use thereof. US20240116877
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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