c-Kit-IN-8

c-Kit-IN-8

• CAS Number: 2941024-89-9
• UNSPSC Description: c-Kit-IN-8 (Compound 53) is an inhibitor for c-Kit kinase, that inhibits uKIT kinase with an IC50 > 1 μM. c-Kit-IN-8 inhibits the proliferation of cancer cell GIST430 and BaF3 wildtype and mutants with IC50 > 0.1 μM[1].
• Target Antigen: c-Kit
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/c-kit-in-8.html
• Smiles: COCCOC1=CC(F)=C2C(N=CN=C2NC3=CC=C(C=C3)NC(CCN4CCCC4=O)=O)=C1
• Molecular Weight: 467.49
• References & Citations: [1]Ahn YM, et al., Kit kinase inhibitors and methods of use thereof. US20240116877,
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported