(S,R,S)-AHPC-(C3-PEG)2-C6-Cl
CAT:
804-HY-103608-04
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: Yes
(S,R,S)-AHPC-(C3-PEG)2-C6-Cl
- CAS Number: 1835705-61-7
- UNSPSC Description: (S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-(C3-PEG)2-C6-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
- Target Antigen: E3 Ligase Ligand-Linker Conjugates
- Type: Reference compound
- Related Pathways: PROTAC
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/E3_ligase_Ligand-Linker_Conjugates_11.html
- Purity: 99.89
- Solubility: DMSO : 200 mg/mL (ultrasonic)|Ethanol : 100 mg/mL (ultrasonic)
- Smiles: O=C(N[C@@H](C(C)(C)C)C(N(C[C@H](O)C1)[C@@H]1C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)=O)CCCCCOCCCCCOCCCCCCCl
- Molecular Weight: 749.44
- References & Citations: [1]Ashton C. Lai, et al. Modular PROTAC Design for the Degradation of Oncogenic BCR-ABL. Angew Chem Int Ed Engl. 2016 Jan 11; 55(2): 807–810.
- Shipping Conditions: Dry Ice
- Storage Conditions: -80°C, protect from light, stored under nitrogen
- Clinical Information: No Development Reported