Sulbactam

• Description:

  Sulbactam (CP45899) is a competitive, irreversible beta-lactamase inhibitor. Sulbactam shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex[1][2].

• Product Name Alternative:

  CP45899

• UNSPSC:

  12352005

• Hazard Statement:

  H302

• Target:

  Antibiotic; Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/Sulbactam.html

• Concentration:

  10mM

• Purity:

  99.75

• Solubility:

  DMSO : ≥ 100 mg/mL|H2O : 20 mg/mL (ultrasonic)

• Smiles:

  O=C([C@@H](C(C)(C)S([C@]1([H])C2)(=O)=O)N1C2=O)O

• Molecular Formula:

  C8H11NO5S

• Molecular Weight:

  233.25

• Precautions:

  H302

• References & Citations:

  [1]Noguchi JK, et al. Sulbactam: a beta-lactamase inhibitor. Clin Pharm. 1988;7 (1) :37-51.|[2]Lin HS, et al. Sulbactam treatment for pneumonia involving multidrug-resistant Acinetobacter calcoaceticus-Acinetobacter baumannii complex. Infect Dis (Lond) . 2015;47 (6) :370-378.|[3]Betrosian AP, et al. Ampicillin-sulbactam: an update on the use of parenteral and oral forms in bacterial infections. Expert Opin Drug Metab Toxicol. 2009;5 (9) :1099-1112.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• Isoform:

  β-lactam

• CAS Number:

  [68373-14-8]