Collagen Type I, Tuna fish

• Background:

  Type I Collagen usually exists as a heterotrimer formed by alpha 1(I) and alpha 2(I) chains and is found in bone, cornea, skin and tendon. In foetal tissues also homotrimers of alpha-1(I) are found, but they are not constituents of normal adult tissues. Collagens consist of a family of highly specialized glycoproteins of which at least 16 genetically distinct types are known to date. The basal unit of a collagen molecule consists of a triple-helical structure formed by 3 alpha-chains. Predominant amino acids are glycine, proline and hydroxproline. Regularly also lysines and hydroxylysines occur, which are responsible for cross-linkage and glycosylation of the protein chains. Different composition of alpha-chains and different glycosylation contribute to the high variability of collagens in different tissues and organs. Tunafish collagen type I.

• Host:

  Rabbit

• Applications:

  IHC (paraffin), IF, ELISA, Radioimmunoassay, WB

• Field of Research:

  Extracellular matrix

• Purification Method:

  affinity purified antibody lyophilized from phosphate buffered solution; no BSA and preservative added!

• Assay Principle:

  IHC(P), IFA, ELISA, RIA, IB/WB

• Concentration:

  1 mg/mL

• Form:

  affinity purified antibody lyophilized from phosphate buffered solution; No BSA and preservative added

• Precautions:

  *These antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in Humans or animals.

• References & Citations:

  1. Rigo C., Hartmann D.J., Bairati A. - Electrophoretic and immunochemeical study of collagens from Sepia officinalis cartilage. Biochim. Biophys. Acta 2002, 1572, 77-84.

• Storage Conditions:

  -20°C