Ethyl Caffeate

CAT: 0804-HY-N6966-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N6966-01Size:5 mg
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse skin[1].
CAS Number
[102-37-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
COX; NF-κB; NO Synthase; PGE synthase
Type
Natural Products
Related Pathways
Immunology/Inflammation; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/ethyl-caffeate.html
Purity
99.34
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C(OCC)/C=C/C1=CC=C(O)C(O)=C1
Molecular Formula
C11H12O4
Molecular Weight
208.21
Precautions
H302, H315, H319, H335
References & Citations
[1]Chiang YM, et al. Ethyl caffeate suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2 in vitro or in mouse skin. Br J Pharmacol. 2005 Oct;146 (3) :352-63.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
COX-2; iNOS; NF-κB

Popular Products