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Taurolidine

CAT: 0804-HY-W011522-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W011522-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Taurolidine is a potent antimicrobial and anticancer agent. Taurolidine inhibits cell proliferation. Taurolidine induces apoptosis and autophagy. Taurolidine rescues mice from sepsis-associated lethality[1][2].
CAS Number
19388-87-5
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Antibiotic; Apoptosis; Autophagy; Bacterial
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis; Autophagy
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/taurolidine.html
Purity
98.19
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
O=S1(NCN(CN(CC2)CNS2(=O)=O)CC1)=O
Molecular Formula
C7H16N4O4S2
Molecular Weight
284.36
Precautions
H315, H319, H335
References & Citations
[1]Marley K, et al. The effects of taurolidine alone and in combination with doxorubicin or carboplatin in canine osteosarcoma in vitro. BMC Vet Res. 2013 Jan 18;9:15. doi: 10.1186/1746-6148-9-15.|[2]Huang J, et al. Autophagy induced by taurolidine protects against polymicrobial sepsis by promoting both host resistance and disease tolerance. Proc Natl Acad Sci U S A. 2022 May 10;119 (19) :e2121244119.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched