Imperatorin (Standard)

CAT: 0804-HY-N0285R-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N0285R-01Size:5 mg
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Description
Imperatorin (Standard) is the analytical standard of Imperatorin. This product is intended for research and analytical applications. Imperatorin is an effective of NO synthesis inhibitor (IC50=9.2 μmol), which also is a BChE inhibitor (IC50=31.4 μmol) . Imperatorin is a weak agonist of TRPV1 with EC50 of 12.6±3.2 μM.
CAS Number
[482-44-0]
Product Name Alternative
Ammidin (Standard)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Cholinesterase (ChE) ; Reference Standards; TRP Channel
Type
Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/imperatorin-standard.html
Purity
98.77
Smiles
O=C1C=CC2=CC3=C(OC=C3)C(OC/C=C(C)/C)=C2O1
Molecular Formula
C16H14O4
Molecular Weight
270.28
Precautions
H302, H315, H319, H335
References & Citations
[1]Kozio? E, et al. Imperatorin-pharmacological meaning and analytical clues: profound investigation. Phytochem Rev. 2016;15:627-649.|[2]Chen X, et al. Furanocoumarins are a novel class of modulators for the transient receptor potential vanilloid type 1 (TRPV1) channel. J Biol Chem. 2014 Apr 4;289 (14) :9600-10.|[3]Budzynska B, et al. Effects of imperatorin on scopolamine-induced cognitive impairment and oxidative stress in mice. Psychopharmacology (Berl) . 2015 Mar;232 (5) :931-42.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards

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