Imperatorin (Standard)

• Description:

  Imperatorin (Standard) is the analytical standard of Imperatorin. This product is intended for research and analytical applications. Imperatorin is an effective of NO synthesis inhibitor (IC50=9.2 μmol), which also is a BChE inhibitor (IC50=31.4 μmol) . Imperatorin is a weak agonist of TRPV1 with EC50 of 12.6±3.2 μM.

• Product Name Alternative:

  Ammidin (Standard)

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Cholinesterase (ChE) ; Reference Standards; TRP Channel

• Type:

  Reference Standards

• Related Pathways:

  Membrane Transporter/Ion Channel; Neuronal Signaling; Others

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/imperatorin-standard.html

• Purity:

  98.77

• Smiles:

  O=C1C=CC2=CC3=C(OC=C3)C(OC/C=C(C)/C)=C2O1

• Molecular Formula:

  C16H14O4

• Molecular Weight:

  270.28

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Kozio? E, et al. Imperatorin-pharmacological meaning and analytical clues: profound investigation. Phytochem Rev. 2016;15:627-649.|[2]Chen X, et al. Furanocoumarins are a novel class of modulators for the transient receptor potential vanilloid type 1 (TRPV1) channel. J Biol Chem. 2014 Apr 4;289 (14) :9600-10.|[3]Budzynska B, et al. Effects of imperatorin on scopolamine-induced cognitive impairment and oxidative stress in mice. Psychopharmacology (Berl) . 2015 Mar;232 (5) :931-42.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, sealed storage, away from light and moisture

• Scientific Category:

  Reference Standards

• CAS Number:

  [482-44-0]