Dithizone

• Description:

  Dithizone can be toxic to pancreatic islet cells and cause experimental diabetes. Dithizone can be used for in vitro in vivo staining of transplanted islets and cytoplasmic granules of bone marrow cells. Dithizone can be used as a chelating agent and colorimetric indicator for the detection and extraction of various heavy metals, including lead and mercury, in analytical and biochemical applications. Dithizone forms stable colored complexes with metal ions and can be quantitatively analyzed by methods such as spectrophotometry[1][2].

• Product Name Alternative:

  Diphenylthiocarbazone

• UNSPSC:

  12352200

• Hazard Statement:

  H315, H319

• Target:

  Biochemical Assay Reagents

• Type:

  Biochemical Assay Reagents

• Related Pathways:

  Others

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/dithizone.html

• Solubility:

  DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  S=C(/N=N/C1=CC=CC=C1)NNC2=CC=CC=C2

• Molecular Formula:

  C13H12N4S

• Molecular Weight:

  256.33

• Precautions:

  H315, H319

• References & Citations:

  [1]Clark SA, et al. Staining and in vitro toxicity of dithizone with canine, porcine, and bovine islets. Cell Transplant. 1994 Jul-Aug;3 (4) :299-306.|[2]MCNARY WF Jr. Dithizone staining of myeloid granules. Blood. 1957 Jul;12 (7) :644-8.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, stored under nitrogen)

• Scientific Category:

  Biochemical Assay Reagents

• Clinical Information:

  No Development Reported

• CAS Number:

  60-10-6