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Odiparcil

CAT: 0804-HY-10277-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-10277-01Size:5 mg
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Description
Odiparcil (SB-424323) is an orally active β-D-xyloside derivative. Odiparcil can effectively divert the synthesis of cellular glycosaminoglycans (GAG) into secreted soluble species and reduce GAG accumulation. Odiparcil shows antithrombin and antiplatelet activity. Odiparcil can be used for the researches of metabolic and cardiovascular disease, such as mucopolysaccharidoses (MPS) and thrombosis[1][2].
CAS Number
137215-12-4
Product Name Alternative
SB-424323
UNSPSC
12352005
Target
Thrombin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/odiparcil.html
Purity
99.98
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C1=CC=C(O[C@H]2[C@@H]([C@H]([C@@H](CS2)O)O)O)C=C1O3)=CC3=O
Molecular Formula
C15H16O6S
Molecular Weight
324.35
References & Citations
[1]Entchev E, et al. Odiparcil, a potential glycosaminoglycans clearance therapy in mucopolysaccharidosis VI-Evidence from in vitro and in vivo models. PLoS One. 2020 May 15;15 (5) :e0233032.|[2]Toomey JR, et al. A comparison of the beta-D-xyloside, odiparcil, to warfarin in a rat model of venous thrombosis. J Thromb Haemost. 2006 Sep;4 (9) :1989-96.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

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