PCK1 Polyclonal Antibody

CAT: 0763-D-AB-10224L-01Size: 25 µLDry Ice: NoHazardous: No

1 / 3

CAT#:0763-D-AB-10224L-01Size:25 µL

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Background

This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.

Abbreviation

PCK1

UniProt

P07379

Host

Rabbit

Reactivity

Human; Rat

Immunogen

Recombinant Rat PCK1 protein expressed by E.coli

Target

Cytosolic [GTP]; GTP; PCK1; PCKGC; PEP carboxykinase; PEPCK-C; PEPCK1; PEPCKC; Phosphoenolpyruvate carboxykinase 1 (soluble) ; Phosphoenolpyruvate carboxykinase 1; Phosphoenolpyruvate carboxykinase; Phosphoenolpyruvate carboxykinase; cytosolic [GTP]; Phosphoenolpyruvate carboxykinase; cytosolic; Phosphoenolpyruvate carboxylase; Phosphopyruvate carboxylase; PCK1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Cardiovascular; Metabolism; Signal Transduction

Purification

Antigen Affinity Purification

Concentration

1 mg/mL

Dilution

IHC 1:100-1:200

Buffer

PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

UniProtKB · P07379

Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

PCKGC_RAT · Rattus norvegicus

View on UniProt ↗

Primary accession: P07379
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: Pck1
Protein existence: 1: Evidence at protein level
Organism: Rattus norvegicus (Rat)
Taxonomy ID: 10116
Alternative names: PEPCK-C
EC number: 4.1.1.32
Processing: —
Secondary accessions: —

Protein keywords

Technical term

3D-structureDirect protein sequencingReference proteome

PTM

AcetylationPhosphoproteinUbl conjugation

Cellular component

CytoplasmEndoplasmic reticulum

Molecular function

DecarboxylaseKinaseLyaseTransferase

Biological process

Gluconeogenesis

Ligand

GTP-bindingManganeseMetal-bindingNucleotide-binding

Product Datasheet

Related Products

Catalog	Name
E-EL-M2433	ELISA kit for Mouse PCK1 (Phosphoenolpyruvate Carboxykinase 1)
E-EL-H1702	ELISA kit for Human PCK1 (Phosphoenolpyruvate Carboxykinase 1)
E-EL-R2424	ELISA kit for Rat PCK1 (Phosphoenolpyruvate Carboxykinase 1)
E-CL-H1069	CLIA kit for Human PCK1 (Phosphoenolpyruvate Carboxykinase 1)
E-AB-62856-01	PCK2 Polyclonal Antibody
E-AB-15206-01	PCK2 Polyclonal Antibody
E-AB-11396-01	PCK2 Polyclonal Antibody
E-AB-92385-01	(KO Validated) PEPCK/PCK2 Polyclonal Antibody
E-AB-65139-01	Polyclonal AntibodyPC1 Polyclonal Antibody
AN301621L-01	Recombinant PCK2 Monoclonal Antibody

Alternative Products

Catalog	Name
MBS2527243-01	PCK1 Polyclonal Antibody
APR08967G	Polyclonal PCK1 Antibody
TA331175	PCK1 Rabbit Polyclonal Antibody
TA303224	PCK1 Goat Polyclonal Antibody
NBP1-80928-25ul	Rabbit Polyclonal PCK1 Antibody