AIP-II

• UNSPSC Description:

  AIP-II is a macrocyclic peptide signaling molecule used for quorum sensing, which can be produced be Staphylococcus aureus. AIP-II binds to AgrC-II receptor, regulates the virulence gene expression in Staphylococcus aureus. AIP-II is an antagonist for AgrC-I receptor[1].

• Target Antigen:

  Bacterial

• Type:

  Peptides

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/aip-ii.html

• Smiles:

  O=C([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CSC1=O)NC([C@H](C)NC([C@H](CC(N)=O)NC([C@H](C(C)C)NC(CN)=O)=O)=O)=O)=O)CO)=O)CO)=O)CC(C)C)N[C@H]1CC2=CC=CC=C2

• Molecular Weight:

  878.99

• References & Citations:

  [1]Tal-Gan Y, et al., Structural characterization of native autoinducing peptides and abiotic analogues reveals key features essential for activation and inhibition of an AgrC quorum sensing receptor in Staphylococcus aureus. J Am Chem Soc. 2013 Dec 11;135(49):18436-44.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  200010-31-7