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Phomoxanthone A

CAT: 0804-HY-126640Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-126640Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Phomoxanthone A is a xanthone dimer, which can be isolated from Phomopsis. Phomoxanthone A exhibits antimalarial and antitubercular activities against Plasmodium falciparum (K1, multidrug-resistant strain, IC50 is 0.11 µg/mL) and Mycobacterium tuberculosis (H37Ra strain, MIC is 0.50 µg/mL) . Phomoxanthone A exhibits cytotoxicity in cells KB, BC-1 and Vero, IC50 is 0.99, 0.51 and 1.4 µg/mL, respectively[1].
CAS Number
359844-69-2
UNSPSC
12352005
Target
Parasite
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/phomoxanthone-a.html
Smiles
O=C1C2=C(O[C@@]3(COC(C)=O)[C@@H](OC(C)=O)[C@@H](C)CC(O)=C31)C(C4=CC=C(O)C5=C4O[C@@]6(COC(C)=O)[C@@H](OC(C)=O)[C@@H](C)CC(O)=C6C5=O)=CC=C2O
Molecular Formula
C38H38O16
Molecular Weight
750.70
References & Citations
[1]Isaka M, et al., Phomoxanthones A and B, novel xanthone dimers from the endophytic fungus Phomopsis species. J Nat Prod. 2001 Aug;64 (8) :1015-8.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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