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Karanjin

CAT: 0804-HY-N2534-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N2534-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Karanjin is an orally active furanoflavonoid which can be isolated from several Leguminosae. Karanjin exhibits evident anti-diabetic, anti-cancer, anti-inflammatory, antioxidant, anticolitis, anti-ulcer, anti-Alzheimer properties and multiple insect repellent/insecticidal, acaricide properties, suggesting the potential of Karanjin to be applied to relevant research[1].
CAS Number
521-88-0
UNSPSC
12352005
Hazard Statement
H302, H312, H315, H319, H332, H335
Target
AMPK; Apoptosis; Cytochrome P450; NF-κB; Phosphatase
Type
Natural Products
Related Pathways
Apoptosis; Epigenetics; Metabolic Enzyme/Protease; NF-κB; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Endocrinology; Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/karanjin.html
Purity
99.90
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C2=CC=C(OC=C3)C3=C2OC(C4=CC=CC=C4)=C1OC
Molecular Formula
C18H12O4
Molecular Weight
292.29
Precautions
H302, H312, H315, H319, H332, H335
References & Citations
[1]Guo JR, et al. Effects of karanjin on cell cycle arrest and apoptosis in human A549, HepG2 and HL-60 cancercells. Biol Res. 2015 Jul 26;48:40.|[2]Jaiswal N, et al.Karanjin from Pongamia pinnata induces GLUT4 translocation in skeletal muscle cells in a phosphatidylinositol-3-kinase-independent manner. Eur J Pharmacol. 2011 Nov 16;670 (1) :22-8.|[3]Singh A, et al. Karanjin. Phytochemistry. 2021, 183:112641.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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