Products for Research Use Only

Policresulen

CAT: 0804-HY-W129596-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W129596-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Policresulen is a competitive inhibitor for DENV2 NS2B/NS3 protease with an IC50 of 0.48 μg/mL. Policresulen can be used as a local hemostatic and antibacterial agent for research of cervical and vaginal inflammation, skin lesions, oral mucosa and gingival inflammation[1][2].
CAS Number
101418-00-2
UNSPSC
12352100
Hazard Statement
H302, H315, H319, H335
Target
Dengue Virus; Virus Protease
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/policresulen.html
Purity
51.6
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
CC1=C(C)C(O)=C(S(=O)(O)=O)C=C1CC.[n]
Molecular Formula
(C8H10O4S) n
Precautions
H302, H315, H319, H335
References & Citations
[1]Wu DW, et al. Policresulen, a novel NS2B/NS3 protease inhibitor, effectively inhibits the replication of DENV2 virus in BHK-21 cells. Acta Pharmacol Sin. 2015;36 (9) :1126-1136. |[2]Zaher A R, et al. Immunohistochemical Expression Of Epithelial Cadherin In The Buccal Mucosa Of Guinea Pigs After Topical Application Of Policresulen[J]. Cairo Dental Journal, 2014, 20: 17-21.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported