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Diphlorethohydroxycarmalol

CAT: 0804-HY-N10413-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N10413-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Diphlorethohydroxycarmalol, a kind of phlorotannin, is an orally active α-glucosidase and α-amylase inhibitor with IC50s of 0.16 mM and 0.53 mM, respectively. Diphlorethohydroxycarmalol has anti-diabetic activities[1].
CAS Number
138529-04-1
UNSPSC
12352005
Target
Glycosidase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/diphlorethohydroxycarmalol.html
Purity
98.46
Solubility
H2O : 10 mg/mL (ultrasonic; warming)
Smiles
OC1=CC(O)=C(OC2=C(O)C(O)=C3OC4=CC(O)=C(OC5=CC(O)=CC(O)=C5)C(O)=C4OC3=C2)C(O)=C1
Molecular Formula
C24H16O13
Molecular Weight
512.38
References & Citations
[1]Soo-Jin Heo, et al. Diphlorethohydroxycarmalol isolated from Ishige okamurae, a brown algae, a potent alpha-glucosidase and alpha-amylase inhibitor, alleviates postprandial hyperglycemia in diabetic mice. Eur J Pharmacol. 2009 Aug 1;615 (1-3) :252-6.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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