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IGFBP7 Polyclonal Antibody

CAT: 0763-D-AB-10467L-01Size: 25 µLDry Ice: NoHazardous: No
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CAT#:0763-D-AB-10467L-01Size:25 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the insulin-like growth factor (IGF) -binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm.
Abbreviation
IGFBP7
UniProt
Q16270
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human IGFBP7 protein expressed by Mammalian
Target
AGM; Angiomodulin; FSTL2; IBP-7; IBP7; IBP7; IGF binding protein 7; IGF-binding protein 7; IGFBP rP1; IGFBP-7; IGFBP-rP1; IGFBP7; IGFBPRP1; Insulin like growth factor binding protein 7; Insulin-like growth factor-binding protein 7; MAC25; MAC25 protein; PGI2 stimulating factor; PGI2-stimulating factor; Prostacyclin stimulating factor; Prostacyclin-stimulating factor; PSF; RAMSVPS; TAF; Tumor-derived adhesion factor
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Signal Transduction
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
IHC 1:100-1:200
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q16270

Insulin-like growth factor-binding protein 7

IBP7_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q16270
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IGFBP7
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IBP-7, IGF-binding protein 7, IGFBP-7
EC number
—
Processing
Precursor
Secondary accessions
B4E1N2, B7Z9W7, Q07822, Q53YE6, Q9UCA8
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicingRNA editing

Biological process

Cell adhesion

PTM

Disulfide bondGlycoproteinPhosphoprotein

Molecular function

Growth factor binding

Domain

Immunoglobulin domainSignal

Cellular component

Secreted
Product Datasheet
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