(3aR,5R,6aS)-5-(((tert-Butyldiphenylsilyl)oxy)methyl)-2,2-dimethyldihydrofuro[2,3-d][1,3]dioxol-6(3aH)-one

CAT:

804-HY-W061531

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CAS Number: 75783-45-8
UNSPSC Description: 5-O-TBDPS-1,2-di-O-isopropy lidene-3-keto-alpha-D-xylofuranoside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen: Nucleoside Antimetabolite/Analog
Type: Reference compound
Related Pathways: Cell Cycle/DNA Damage
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/5-o-tbdps-1-2-di-o-isopropy-lidene-3-keto-alpha-d-xylofuranoside.html
Solubility: 10 mM in DMSO
Smiles: O=C([C@]1([H])[C@](OC(C)(O1)C)([H])O2)[C@H]2CO[Si](C3=CC=CC=C3)(C4=CC=CC=C4)C(C)(C)C
Molecular Weight: 426.58
References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-W061531	(3aR,5R,6aS)-5-(((tert-Butyldiphenylsilyl)oxy)methyl)-2,2-dimethyldihydrofuro[2,3-d][1,3]dioxol-6(3aH)-one
HY-154391	5-O-(tert-Butyldiphenylsilyl)-2,3-isopropylidene-D-ribonolactone
HY-W101130S	2,2-Dimethylbenzo[d][1,3]dioxole-d2
HY-154369	1,4-Anhydro-2,3-O-isopropylidene-5-O-t-butyldiphenylsilyl-4-thio-D-ribitol
HY-W339603	4-O-Acetyl-3,6-di-O-(tert-butyldiphenylsilyl)-D-glucal
HY-N2185-01	(5R,6E)-5-Hydroxy-1,7-diphenyl-6-hepten-3-one
HY-W039180-01	Methyl (tert-butoxycarbonyl)-D-leucinate
HY-N2185-02	(5R,6E)-5-Hydroxy-1,7-diphenyl-6-hepten-3-one
HY-W039758-02	Methyl (tert-butoxycarbonyl)-D-phenylalaninate
HY-W039758-01	Methyl (tert-butoxycarbonyl)-D-phenylalaninate

Cat	Name
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