Platinum-GP Retroviral Packaging Cell Line, Pantropic

Platinum-GP Retroviral Packaging Cell Line, Pantropic

• Description: Conventional cells used for retrovirus packaging, such as those based on NIH3T3 cells, have limited stability and produce relatively low yields of retrovirus, mainly due to the poor expression of retroviral structure proteins (gag, pol and env) in the cells. The Platinum Retroviral Packaging Cell Lines are based on the 293T cell line. They exhibit longer stability and produce higher yields of retroviral structure proteins. Plat-GP cells contain the gag and pol genes required for retroviral packaging; an expression vector is co-transfected with a VSVG envelope vector.
• UNSPSC: 41106514
• Features & Benefits: Higher retroviral yields: average titer 106 to 107 infectious units/mL with transient transfection; Longer stability: up to 4 months in the presence of drug selection; Produce VSVG-pseudotyped pantropic retrovirus, which can easily infect cells of nearly any species
• Shipping Conditions: Dry Ice
• Storage Conditions: For best results begin culture upon receipt. If this is not possible, store at -80C until first culture. Store subsequent cultured cells in liquid nitrogen.