Products for Research Use Only
RegisterLogin

Kobusin

CAT: 0804-HY-N5101-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N5101-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Kobusin is a bisepoxylignan isolated from the Pnonobio biondii Pamp. Kobusin is an activator of CFTR and CaCCgie chloride channels and a inhibitor of ANO1/CaCC (calcium-activated chloride channel) channel[1][2].
CAS Number
36150-23-9
UNSPSC
12352005
Hazard Statement
H302, H361, H372, H410
Target
CFTR; Chloride Channel
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/kobusin.html
Purity
99.93
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC1=CC=C([C@H]2OC[C@]3([H])[C@@H](C4=CC=C(OCO5)C5=C4)OC[C@@]32[H])C=C1OC
Molecular Formula
C21H22O6
Molecular Weight
370.40
Precautions
H302, H361, H372, H410
References & Citations
[1]Yu Jiang , et al. Modulation of Chloride Channel Functions by the Plant Lignan Compounds Kobusin and Eudesmin. Front Plant Sci. 2015 Nov 25;6:1041.|[2]Xing Zhang, et al. Bioassay-guided isolation of bisepoxylignans from the flower buds of Magnolia biondii Pamp and their antiallergic effects. RSC Adv., 2017,7, 34236-34243.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Related Products

CatalogName
HY-149033Kobusine derivative-2
HY-149032Kobusine derivative-1
HY-N3419Kobusone

Alternative Products

CatalogName
574765Kobusin
TRC-K655050-100MG(+)-Kobusin
LBA15023-01(+) -Kobusin

Popular Products