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Kojic acid-13C6

CAT: 0804-HY-W050154SSize: 30 μg (168.84 μM x 1.2 mL in Acetonitrile)Dry Ice: NoHazardous: No
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CAT#:0804-HY-W050154SSize:30 μg (168.84 μM x 1.2 mL in Acetonitrile)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Kojic acid-13C6 is 13C labeled Kojic acid. Kojic acid is a substance produced by Aspergillus oryzae that is orally effective and can also be absorbed transdermally. Kojic acid exhibits various biological activities, including anti-aging, anti-nematode, antimicrobial, antioxidant, and anti-inflammatory effects. Kojic acid is a Tyrosinase inhibitor with an Mushroom Tyrosinase IC50 of 182.7 μM. Kojic acid prevents melanin production by capturing copper ions that bind to the tyrosinase active site, thus inhibiting its activation. Kojic acid also suppresses the NF-κB and p21 signaling pathways in human keratinocytes. Kojic acid derivatives have anticancer activity[1][2][3][4][5][6][7][8].
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Parasite
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/kojic-acid-13c6.html
Concentration
168.84 μM * 1.2 mL in Acetonitrile
Solubility
10 mM in DMSO
Smiles
O=[13C]1[13CH]=[13C]([13CH2]O)O[13CH]=[13C]1O
Molecular Formula
13C6H6O4
Molecular Weight
148.07
References & Citations
[1]Wei X, et al. Kojic acid inhibits senescence of human corneal endothelial cells via NF-κB and p21 signaling pathways. Exp Eye Res. 2018 Dec 28;180:174-183.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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