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GW842166X

CAT: 0804-HY-14167-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14167-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GW842166X is a potent and selective cannabinoid receptor 2 (CB2) agonist with IC50 values of 63 and 91 nM for human and rat CB2, respectively.
CAS Number
666260-75-9
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Cannabinoid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/GW842166X.html
Purity
99.97
Solubility
DMSO : ≥ 83.3 mg/mL
Smiles
ClC1=CC(Cl)=C(NC2=NC=C(C(NCC3CCOCC3)=O)C(C(F)(F)F)=N2)C=C1
Molecular Formula
C18H17Cl2F3N4O2
Molecular Weight
449.25
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Giblin GM, et al. Discovery of 2-[ (2,4-dichlorophenyl) amino]-N-[ (tetrahydro- 2H-pyran-4-yl) methyl]-4- (trifluoromethyl) - 5-pyrimidinecarboxamide, a selective CB2 receptor agonist for the treatment of inflammatory pain. J Med Chem. 2007 May 31;50 (11) :2597-600.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

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