EAAC1 Antibody: APC

• Background:

  SLC1A1/EAAT3/EAAC1, a member of this transporter family, is expressed throughout the body, particularly in brain, intestine, liver, heart and kidney. Functional defects of the SLC1A1 gene are found in patients of dicarboxylicamino aciduria.

• Description:

  Mouse Anti-Human EAAC1 Monoclonal IgG1

• Specifications:

  Detects ~60kDa.

• Product Name Alternative:

  Excitatory amino-acid carrier 1 Antibody, excitatory amino acid transporter 3 Antibody, EAAT3 Antibody, Neuronal and epithelial glutamate transporter Antibody, Sodium-dependent glutamate/aspartate transporter 3 Antibody, solute carrier family 1 member 1 and Slc1a1 Antibody

• Synonyms:

  EAAC1 Antibody, Clone N180/41: APC

• UNSPSC:

  12352203

• Gene ID:

  6505

• Swiss Prot:

  P43005

• Accession Number:

  NP_004161.4

• Cellular Locus:

  Membrane

• Host:

  Mouse

• Species Reactivity:

  Human, Rat

• Immunogen:

  Fusion protein amino acids 1-524 (full length) of human EAAC1

• Target:

  EAAT3

• Clonality:

  Monoclonal

• Isotype:

  IgG1

• Clone:

  N180/41 (Formerly sold as S180-41)

• Conjugation:

  APC

• Validated Applications:

  IHC, ICC/IF

• Purification:

  Protein G Purified

• Limit Of Detection:

  5 µg of SMC-406 was sufficient for immunoprecipitation of EAAC1 from 50 µg of rat brain lysate.

• Concentration:

  1 mg/ml

• Dilution:

  WB (1:1000), ICC/IF (1:100);optimal dilutions for assays should be determined by the user.

• Weight:

  0.1

• Buffer:

  95.64mM Phosphate, 2.48mM MES and 2mM EDTA

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Smith C. P., et al., (1994) Genomics 20:335-336. 2. Kanai Y., and Hediger M. A. (1992) Nature 360:467-471.

• CAS Number:

  9007-83-4