GABA-A Receptor Beta 3 Antibody: PerCP

GABA-A Receptor Beta 3 Antibody: PerCP

• Background: The GABA-A receptor is a member of the superfamily of fast acting ligand-gated ion channels. The individual subunits of these receptors have similar sequences and structural features (1). GABA-A receptors are the major fast inhibitory neurotransmitter gated ion channels in the brain (2).
• Description: Mouse Anti-Mouse GABA-A Receptor Beta 3 Monoclonal IgG1
• Specifications: Detects ~55kDa. No cross-reactivity against GABA-A-R-Beta 2 or –Beta1.
• Alternative Name: ECA5 antibody, GABA alpha receptor beta-2 subunit antibody, GABA(A) receptor subunit beta-3 antibody, GABAA receptor beta 3 subunit antibody, GABAA receptor subunit beta 3 antibody, GABR B3 antibody, Gabrb3 antibody, Gamma aminobutyric acid (GABA) A receptor beta 3 antibody, Gamma aminobutyric acid receptor subunit beta 3 antibody, Gamma-aminobutyric acid receptor subunit beta-3 antibody, GBRB3_HUMAN antibody, MGC9051 antibody
• Synonyms: GABA A Receptor Beta 3 Antibody, Clone N87/25: PerCP
• UNSPSC: 12352203
• Gene ID: 14402
• Swiss Prot: P63080
• Accession Number: NP_032097.1
• Cellular Locus: Cell Membrane | Cell Junction | Synapse | Postsynaptic Cell Membrane
• Host: Mouse
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Fusion protein amino acids 370-433 of mouse GABA-A-R-Beta 3
• Target: GABA A Receptor
• Clonality: Monoclonal
• Isotype: IgG1
• Clone: N87/25 (Formerly sold as S87-25)
• Conjugation: PerCP
• Validated Applications: WB, IHC, ICC/IF, ELISA
• Purification: Protein G Purified
• Limit Of Detection: 1 µg/ml of SMC-339 was sufficient for detection of Beta 3 GABA receptor in 10 µg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
• Concentration: 1 mg/ml
• Dilution: WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
• Weight: 0.1
• Buffer: 95.64mM Phosphate, 2.48mM MES and 2mM EDTA
• Precautions: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
• References & Citations: 1. Bracamontes J.R. and Steinbach J.H. (2008) J Bio Chem. 283: 26128-26136. 2. Macdonald R.L., Olsen R.W. (1993) Annu Rev Neurosci. 17: 569-602.