HPK1-IN-4

HPK1-IN-4

• CAS Number: 2739844-28-9
• UNSPSC Description: HPK1-IN-4 (comp 22) is a HPK1 (MAPK41) inhibitor (IC50 of 0.061 nM) as preclinical immunoresearch tool compound[1].
• Target Antigen: MAP4K
• Type: Reference compound
• Related Pathways: MAPK/ERK Pathway
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/hpk1-in-4.html
• Smiles: COC1=C(NC2=NC=C(C(N)=O)C(NC3=CC=CC=C3CO)=N2)C=C4CN(C)CCC4=C1
• Molecular Weight: 434.49
• References & Citations: [1]Brandon A Vara, et al. Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotherapy Tool Compounds. ACS Med Chem Lett. 2021 Mar 19;12(4):653-661.
• Shipping Conditions: Room Temperature