Ponesimod

• Description :

  Ponesimod is a potent agonist of sphingosine-1-phosphate receptor 1 (S1P1) receptor. It reduces the circulating lymphocytes at a dose of 3-100 mg/kg in a rat model. It selectively activates S1P1 in a GTPγS assay with an EC₅₀ of 5.7 nM. It has been recently approved for the treatment of multiple sclerosis.

• Shipping Conditions :

  Gel Pack

• Storage Conditions :

  -20ºC

• Shelf Life :

  36 months