Amitraz

• UNSPSC Description:

  Amitraz is a non-systemic acaricide and insecticide with alpha-adrenergic agonist activity that interacts with octopamine receptors in the central nervous system and inhibits monoamine oxidase and prostaglandin synthesis[1][2].

• Target Antigen:

  Adrenergic Receptor; Monoamine Oxidase; Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection;GPCR/G Protein;Neuronal Signaling

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/Amitraz.html

• Purity:

  99.65

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CN(/C=N/C1=CC=C(C)C=C1C)/C=N/C2=CC=C(C)C=C2C

• Molecular Weight:

  293.41

• References & Citations:

  [1]Mangia C, et al. Exposure to amitraz, fipronil and permethrin affects cell viability and ABC transporter gene expression in an Ixodes ricinus cell line. Parasit Vectors. 2018 Jul 31;11(1):437. |[2]Kim JC, et al. Evaluation of developmental toxicity of amitraz in Sprague-Dawley rats. Arch Environ Contam Toxicol. 2007 Jan;52(1):137-44.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  33089-61-1