Amitraz

• Description :

  Amitraz is a non-systemic acaricide and insecticide with alpha-adrenergic agonist activity that interacts with octopamine receptors in the central nervous system and inhibits monoamine oxidase and prostaglandin synthesis[1][2].

• Product Name Alternative :

  BTS-27419

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H317, H373

• Target :

  Adrenergic Receptor; Monoamine Oxidase; Parasite

• Type :

  Reference compound

• Related Pathways :

  Anti-infection; GPCR/G Protein; Neuronal Signaling

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection; Endocrinology

• Assay Protocol :

  https://www.medchemexpress.com/Amitraz.html

• Purity :

  99.65

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  CN(/C=N/C1=CC=C(C)C=C1C)/C=N/C2=CC=C(C)C=C2C

• Molecular Formula :

  C19H23N3

• Molecular Weight :

  293.41

• Precautions :

  H302, H317, H373

• References & Citations :

  [1]Mangia C, et al. Exposure to amitraz, fipronil and permethrin affects cell viability and ABC transporter gene expression in an Ixodes ricinus cell line. Parasit Vectors. 2018 Jul 31;11 (1) :437. |[2]Kim JC, et al. Evaluation of developmental toxicity of amitraz in Sprague-Dawley rats. Arch Environ Contam Toxicol. 2007 Jan;52 (1) :137-44.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Mite

• CAS Number :

  [33089-61-1]