Bacoside A3

• Description:

  Bacoside A3 is a triterpenoid saponin isolated from Bacopa monnieri. Bacoside A3 has neuroprotective activity, downregulating β-amyloid-induced inflammatory responses and inhibiting neuronal apoptosis. Bacoside A3 can be used in the study of Alzheimer's disease[1][2].

• UNSPSC:

  12352005

• Hazard Statement:

  H301+H311+H331

• Target:

  Apoptosis; COX; NO Synthase

• Type:

  Natural Products

• Related Pathways:

  Apoptosis; Immunology/Inflammation

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/bacoside-a3.html

• Purity:

  99.85

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  C[C@]12[C@@]34[C@@](CC[C@]1([H])[C@@]5([C@@](C(C)([C@@H](O[C@@]6([H])[C@@H]([C@H]([C@H](O)[C@@H](CO)O6)O[C@]7([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]7O)CO)O[C@]8([H])O[C@@H](CO)[C@H](O)[C@H]8O)CC5)C)([H])CC2)C)([H])[C@]9([H])[C@@](OC4)(O[C@@H](/C=C(C)/C)C[C@@]9(O)C)C3

• Molecular Formula:

  C47H76O18

• Molecular Weight:

  929.10

• Precautions:

  H301+H311+H331

• References & Citations:

  [1]Vini C Sekhar, et al. Insights Into the Molecular Aspects of Neuroprotective Bacoside A and Bacopaside I. Curr Neuropharmacol. 2019;17 (5) :438-446.|[2]Bai Q, et al. Isolation and neuronal apoptosis inhibitory property of bacoside‐A3 via downregulation of β‐amyloid induced inflammatory response[J]. Biotechnology and applied biochemistry, 2022, 69 (2) : 726-734.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  157408-08-7