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Bacoside A3

CAT: 0804-HY-N5064-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N5064-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bacoside A3 is a triterpenoid saponin isolated from Bacopa monnieri. Bacoside A3 has neuroprotective activity, downregulating β-amyloid-induced inflammatory responses and inhibiting neuronal apoptosis. Bacoside A3 can be used in the study of Alzheimer's disease[1][2].
CAS Number
157408-08-7
UNSPSC
12352005
Hazard Statement
H301+H311+H331
Target
Apoptosis; COX; NO Synthase
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bacoside-a3.html
Purity
99.85
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@]12[C@@]34[C@@](CC[C@]1([H])[C@@]5([C@@](C(C)([C@@H](O[C@@]6([H])[C@@H]([C@H]([C@H](O)[C@@H](CO)O6)O[C@]7([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]7O)CO)O[C@]8([H])O[C@@H](CO)[C@H](O)[C@H]8O)CC5)C)([H])CC2)C)([H])[C@]9([H])[C@@](OC4)(O[C@@H](/C=C(C)/C)C[C@@]9(O)C)C3
Molecular Formula
C47H76O18
Molecular Weight
929.10
Precautions
H301+H311+H331
References & Citations
[1]Vini C Sekhar, et al. Insights Into the Molecular Aspects of Neuroprotective Bacoside A and Bacopaside I. Curr Neuropharmacol. 2019;17 (5) :438-446.|[2]Bai Q, et al. Isolation and neuronal apoptosis inhibitory property of bacoside‐A3 via downregulation of β‐amyloid induced inflammatory response[J]. Biotechnology and applied biochemistry, 2022, 69 (2) : 726-734.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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