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Etevritamab

CAT: 0804-HY-P99948-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99948-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Etevritamab (AMG-596) is a bispecific T-cell engager targeting EGFRvIII and CD3. Etevritamab can simultaneously bind to the tumor-specific antigen EGFRvIII on glioblastoma multiforme and CD3 on T cells, thereby activating T-cell proliferation and secretion of cytotoxic substances to induce lysis of the bound tumor cells. Etevritamab can be used for the research of tumors such as glioblastoma multiforme[1][2].
CAS Number
2329692-74-0
Product Name Alternative
AMG-596
UNSPSC
12352203
Target
CD3; EGFR
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/etevritamab.html
Purity
97.00
Smiles
[Etevritamab]
Molecular Weight
(54.66 kDa)
References & Citations
[1]Etevritamab|[2]Sternjak A, et al. Preclinical Assessment of AMG 596, a Bispecific T-cell Engager (BiTE) Immunotherapy Targeting the Tumor-specific Antigen EGFRvIII. Mol Cancer Ther. 2021 May;20 (5) :925-933.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported

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