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WNK4 Polyclonal Antibody

CAT: 0749-ABP60921-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP60921-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
WNK4 (WNK Lysine Deficient Protein Kinase 4) encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K (+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in WNK4 result in pseudohypoaldosteronism type IIB.
Description
Rabbit Anti-WNK4 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Serine/threonine-protein kinase WNK4; Protein kinase lysine-deficient 4; Protein kinase with no lysine 4
Gene ID
65266
Accession Number
Q96J92
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human WNK4 protein
Clonality
Polyclonal
Tag
WNK4
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
136kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of WNK4 protein
Observed Molecular Weight
136
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Serine/threonine-protein kinase WNK4; Protein kinase lysine-deficient 4; Protein kinase with no lysine 4
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q96J92
Isotype
Rabbit IgG

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