VMAT2 Polyclonal Antibody

• Background:

  The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (summary by Peter et al. 1993 [PubMed 7905859]) . See also SLC18A1 (MIM 193002) .

• Description:

  Rabbit Anti-VMAT2 Polyclonal Antibody

• Product Name Alternative:

  Monoamine transporter; Solute carrier family 18 member 2; Vesicular amine transporter 2; VAT2

• Gene ID:

  6571

• Accession Number:

  Q05940

• Reactivity:

  Human, Rat, Mouse

• Immunogen:

  Synthesized peptide derived from part region of human VMAT2 protein at amino acid sequence of 1-80

• Clonality:

  Polyclonal

• Tag:

  VMAT2

• Applications:

  WB, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  56kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  The antibody detects endogenous levels of VMAT2 protein

• Observed Molecular Weight:

  56

• Formulation:

  Liquid solution

• Buffer pH:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names:

  Monoamine transporter; Solute carrier family 18 member 2; Vesicular amine transporter 2; VAT2

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/Q05940

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG