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UBP34 Polyclonal Antibody

CAT: 0749-ABP60836-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP60836-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
USP34 (Ubiquitin Specific Peptidase 34) is a Protein Coding gene. Among its related pathways are Deubiquitination and Signaling by Wnt. Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1) -mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Description
Rabbit Anti-UBP34 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Ubiquitin carboxyl-terminal hydrolase 34; Deubiquitinating enzyme 34; Ubiquitin thioesterase 34; Ubiquitin-specific-processing protease 34
Gene ID
9736
Accession Number
Q70CQ2
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human UBP34 protein
Clonality
Polyclonal
Tag
UBP34
Applications
IHC, IF
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
390kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of UBP34 protein
Observed Molecular Weight
390
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300; IF 1:50-200
Other Product Names
Ubiquitin carboxyl-terminal hydrolase 34; Deubiquitinating enzyme 34; Ubiquitin thioesterase 34; Ubiquitin-specific-processing protease 34
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q70CQ2
Isotype
Rabbit IgG

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