UBE2K Polyclonal Antibody

CAT: 0749-ABP60821-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP60821-01Size:30 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
UBE2K (Ubiquitin Conjugating Enzyme E2 K) is a Protein Coding gene. Among its related pathways are Protein ubiquitination and Class I MHC mediated antigen processing and presentation. The protein encoded by UBE2K belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for UBE2K.
Description
Rabbit Anti-UBE2K Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Ubiquitin-conjugating enzyme E2 K; E2 ubiquitin-conjugating enzyme K; Huntingtin-interacting protein 2; HIP-2; Ubiquitin carrier protein; Ubiquitin-conjugating enzyme E2-25 kDa; Ubiquitin-conjugating enzyme E2-25K; Ubiquitin-protein ligase
Gene ID
3093
Accession Number
P61086
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human UBE2K protein
Clonality
Polyclonal
Tag
UBE2K
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
22kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of UBE2K protein
Observed Molecular Weight
22
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Ubiquitin-conjugating enzyme E2 K; E2 ubiquitin-conjugating enzyme K; Huntingtin-interacting protein 2; HIP-2; Ubiquitin carrier protein; Ubiquitin-conjugating enzyme E2-25 kDa; Ubiquitin-conjugating enzyme E2-25K; Ubiquitin-protein ligase
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P61086
Isotype
Rabbit IgG

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