UB2D3 Polyclonal Antibody

CAT: 0749-ABP60807-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP60807-01Size:30 µL
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Background
UBE2D3 (Ubiquitin Conjugating Enzyme E2 D3) is a Protein Coding gene. Diseases associated with UBE2D3 include Retinitis Pigmentosa 42. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Protein processing in endoplasmic reticulum. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D3 encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.
Description
Rabbit Anti-UB2D3 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Ubiquitin-conjugating enzyme E2 D3; E2 ubiquitin-conjugating enzyme D3; Ubiquitin carrier protein D3; Ubiquitin-conjugating enzyme E2-17 kDa 3; Ubiquitin-protein ligase D3
Gene ID
7323
Accession Number
P61077
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human UB2D3 protein
Clonality
Polyclonal
Tag
UB2D3
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
16kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of UB2D3 protein
Observed Molecular Weight
16
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Ubiquitin-conjugating enzyme E2 D3; E2 ubiquitin-conjugating enzyme D3; Ubiquitin carrier protein D3; Ubiquitin-conjugating enzyme E2-17 kDa 3; Ubiquitin-protein ligase D3
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P61077
Isotype
Rabbit IgG

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